Research output - O'Brien Institute

  1. Zdolsek, J. M., Morrison, W. A., Dingle, A. M., Palmer, J. A., Penington, A. J., and Mitchell, G. M. (2011) An "off the shelf" vascular allograft supports angiogenic growth in three-dimensional tissue engineering. J Vasc Surg 53, 435-444
  2. Tilkorn, D. J., Lokmic, Z., Chaffer, C. L., Mitchell, G. M., Morrison, W. A., and Thompson, E. W. (2010) Disparate Companions: Tissue Engineering Meets Cancer Research. Cells Tissues Organs 192, 141-157
  3. Stillaert, F., Abberton, K., Keramidaris, E., Thompson, E. W., Blondeel, P., and Morrison, W. A. (2010) Intrinsics and dynamics of fat grafts: an in vivo study. Plastic and Reconstructive Surgery 126, 1155-1162Hamid, Z. A., Blencowe, A., Ozcelik, B., Palmer, J. A., Stevens, G. W., Abberton, K. M., Morrison, W. A., Penington, A. J., and Qiao, G. G. (2010) Epoxy-amine synthesised hydrogel scaffolds for soft-tissue engineering. Biomaterials 31, 6454-6467
  4. Choi, Y. S., Matsuda, K., Dusting, G. J., Morrison, W. A., and Dilley, R. J. (2010) Engineering cardiac tissue in vivo from human adipose-derived stem cells. Biomaterials 31, 2236-2242
  5. Choi, Y. S., Dusting, G. J., Stubbs, S., Arunothayaraj, S., Han, X. L., Collas, P., Morrison, W. A., and Dilley, R. J. (2010) Differentiation of human adipose-derived stem cells into beating cardiomyocytes. J Cell Mol Med 14, 878-889
  6. Morrison, W. A. (2009) Progress in tissue engineering of soft tissue and organs. Surgery 145, 127-130
  7. Koh, C. E., and Morrison, W. A. (2009) Functional impairment after latissimus dorsi flap. ANZ J Surg 79, 42-47
  8. Findlay, M. W., Messina, A., Thompson, E. W., and Morrison, W. A. (2009) Long-term persistence of tissue-engineered adipose flaps in a murine model to 1 year: an update. Plastic and Reconstructive Surgery 124, 1077-1084
  9. Cronin, K. J., Messina, A., Thompson, E. W., Morrison, W. A., Stevens, G. W., and Knight, K. R. (2009) Retraction. The role of biological extracellular matrix scaffolds in vascularized three-dimensional tissue growth in vivo. J Biomed Mater Res B Appl Biomater 89B, 575
  10. Craft, R. O., Rophael, J., Morrison, W. A., Vashi, A. V., Mitchell, G. M., and Penington, A. J. (2009) Effect of local, long-term delivery of platelet-derived growth factor (PDGF) on injected fat graft survival in severe combined immunodeficient (SCID) mice. Journal of Plastic Reconstructive and Aesthetic Surgery 62, 235-243
  11. Vashi, A. V., Keramidaris, E., Abberton, K. M., Morrison, W. A., Wilson, J. L., O'Connor, A. J., Cooper-White, J. J., and Thompson, E. W. (2008) Adipose differentiation of bone marrow-derived mesenchymal stem cells using Pluronic F-127 hydrogel in vitro. Biomaterials 29, 573-579
  12. Hemmrich, K., Van de Sijpe, K., Rhodes, N. P., Hunt, J. A., Di Bartolo, C., Pallua, N., Blondeel, P., and von Heimburg, D. (2008) Autologous in vivo adipose tissue engineering in hyaluronan-based gels--a pilot study. Journal of Surgical Research 144, 82-88
  13. Hachisuka, H., Dusting, G. J., Abberton, K. M., Morrison, W. A., and Jiang, F. (2008) Role of NADPH oxidase in tissue growth in a tissue engineering chamber in rats. Journal of Tissue Engineering and Regenerative Medicine 2, 430-435.
  14. Hemmrich K ,Thomas GP, Abberton KM, McCombe D, Penington AJ, Thompson EW, Morrison WA. MCP-1 and NO promote adipogenesis in a model that mimics obesity. Obesity.2008 15(12):2951-7.
  15. Thomas GP, Hemmrich K, Abberton KM, McCombe D, Penington AJ, Thompson EW, Morrison WA.  Zymosan-induced inflammation stimulates neo-adipogenesis. Int J Obes (Lond). 2008 Feb;32(2):239-48
  16. Di Bella, C., Farlie, P., and Penington, A. J. (2008) Bone regeneration in a rabbit critical-sized skull defect using autologous adipose-derived cells. Tissue Eng Part A 14, 483-490
  17. Abberton, K. M., Bortolotto, S. K., Woods, A. A., Findlay, M., Morrison, W. A., Thompson, E. W., and Messina, A. (2008) Myogel, a novel, basement membrane-rich, extracellular matrix derived from skeletal muscle, is highly adipogenic in vivo and in vitro. Cells Tissues Organs 188, 347-358
  18. Wosnitza, M., Hemmrich, K., Groger, A., Graber, S., and Pallua, N. (2007) Plasticity of human adipose stem cells to perform adipogenic and endothelial differentiation. Differentiation 75, 12-23
  19. Stillaert, F., Findlay, M., Palmer, J., Idrizi, R., Cheang, S., Messina, A., Abberton, K., Morrison, W., and Thompson, E. W. (2007) Host rather than graft origin of Matrigel-induced adipose tissue in the murine tissue-engineering chamber. Tissue Engineering 13, 2291-2300
  20. Rophael, J. A., Craft, R. O., Palmer, J. A., Hussey, A. J., Thomas, G. P., Morrison, W. A., Penington, A. J., and Mitchell, G. M. (2007) Angiogenic growth factor synergism in a murine tissue engineering model of angiogenesis and adipogenesis. American Journal of Pathology 171, 2048-2057
  21. Retraction, Cronin, K. J., Messina, A., Thompson, E. W., Morrison, W. A., Stevens, G. W., and Knight, K. R. (2007) The role of biological extracellular matrix scaffolds in vascularized three-dimensional tissue growth in vivo. J Biomed Mater Res B Appl Biomater 82, 122-128
  22. Peshavariya, H. M., Dusting, G. J., and Selemidis, S. (2007) Analysis of dihydroethidium fluorescence for the detection of intracellular and extracellular superoxide produced by NADPH oxidase. Free Radical Research 41, 699-712. (Citations = 619)
  23. Lokmic, Z., Stillaert, F., Morrison, W. A., Thompson, E. W., and Mitchell, G. M. (2007) An arteriovenous loop in a protected space generates a permanent, highly vascular, tissue-engineered construct. Faseb J 21, 511-522 (Citation = 528)
  24. Hemmrich, K., Thomas, G. P. L., Wosnitza, M., Von Heimburg, D., Morrison, W. A., and Pallua, N. (2007) The isolation and expansion of primary preadipocytes. International Journal of Adipose Tissue In Press
  25. Hemmrich, K., Thomas, G. P. L., Gummersbach, C., Abberton, K., Penington, A., and Morrison, W. A. (2007) Inflammation causes neo-adipogenesis - what adipose tissue engineering can learn from the pathogenesis of obesity. In Chirurgishches Forum 2007 pp. 36, 303-330, Springer
  26. Dolderer, J. H., Abberton, K. M., Thompson, E. W., Slavin, J. L., Stevens, G. W., Penington, A. J., and Morrison, W. A. (2007) Spontaneous large volume adipose tissue generation from a vascularized pedicled fat flap inside a chamber space. Tissue Engineering 13, 673-681
  27. Cronin, K. J., Messina, A., Thompson, E. W., Morrison, W. A., Stevens, G. W., and Knight, K. R. (2007) The role of biological extracellular matrix scaffolds in vascularized three-dimensional tissue growth in vivo. J Biomed Mater Res B Appl Biomater 82, 122-128
  28. Brown, D. L., and Penington, A. J. (2007) Murine skin flap survival may not be affected by underlying fat viability. Journal of Plastic, Reconstructive & Aesthetic Surgery 60, 294-299
  29. Vashi, A. V., Abberton, K. M., Thomas, G. P., Morrison, W. A., O'Connor, A. J., Cooper-White, J. J., and Thompson, E. W. (2006) Adipose tissue engineering based on the controlled release of fibroblast growth factor-2 in a collagen matrix. Tissue Engineering 12, 3035-3043
  30. Stillaert, F. B., Blondeel, P., Hamdi, M., Abberton, K., Thompson, E. W., and Morrison, W. A. (2006) Adipose tissue induction in vivo. Advances in Experimental Medicine and Biology 585, 403-412
  31. Morritt, A. N., Grinsell, D., and Morrison, W. A. (2006) Postmastectomy breast reconstruction using a microvascular breast-sharing technique. Plastic and Reconstructive Surgery 118, 1313-1316; discussion 1317-1319
  32. Morrison, W. A., and Hussey, A. J. (2006) Extracellular matrix as a bioactive material for soft tissue reconstruction. ANZ Journal of Surgery 76, 1047
  33. Kelly, J. L., Findlay, M. W., Knight, K. R., Penington, A., Thompson, E. W., Messina, A., and Morrison, W. A. (2006) Contact with existing adipose tissue is inductive for adipogenesis in matrigel. Tissue Engineering 12, 2041-2047
  34. Hemmrich, K., and von Heimburg, D. (2006) Biomaterials for adipose tissue engineering. Expert Review of Medical Devices 3, 635-645
  35. Hemmrich, K., Meersch, M., Wiesemann, U., Salber, J., Klee, D., Gries, T., and Pallua, N. (2006) Polyesteramide-derived nonwovens as innovative degradable matrices support preadipocyte adhesion, proliferation, and differentiation. Tissue Engineering 12, 3557-3565
  36. Hemmrich, K., Meersch, M., von Heimburg, D., and Pallua, N. (2006) Applicability of the dyes CFSE, CM-DiI and PKH26 for tracking of human preadipocytes to evaluate adipose tissue engineering. Cells Tissues Organs 184, 117-127
  37. Hemmrich, K., Gummersbach, C., Pallua, N., Luckhaus, C., and Fehsel, K. (2006) Clozapine enhances differentiation of adipocyte progenitor cells. Molecular Psychiatry 11, 980-981
  38. Cao, Y., Mitchell, G. M., Messina, A., Price, L., Thompson, E. W., Penington, A., Morrison, W. A., O'Connor, A., Stevens, G., and Cooper-White, J. (2006) The influence of architecture on degradation and tissue ingrowth into three-dimensional poly(lactic-co-glycolic acid) scaffolds in vitro and in vivo. Biomaterials 27, 2854-2864 (Citation = 2823)
  39. von Heimburg, D., Hemmrich, K., Zachariah, S., Staiger, H., and Pallua, N. (2005) Oxygen consumption in undifferentiated versus differentiated adipogenic mesenchymal precursor cells. Respir Physiol Neurobiol 146, 107-116
  40. Hemmrich, K., von Heimburg, D., Cierpka, K., Haydarlioglu, S., and Pallua, N. (2005) Optimization of the differentiation of human preadipocytes in vitro. Differentiation 73, 28-35
  41. von Heimburg, D., Hemmrich, K., Haydarlioglu, S., Staiger, H., and Pallua, N. (2004) Comparison of viable cell yield from excised versus aspirated adipose tissue. Cells Tissues Organs 178, 87-92
  42. Tester, A. M., Waltham, M., Oh, S. J., Bae, S. N., Bills, M. M., Walker, E. C., Kern, F. G., Stetler-Stevenson, W. G., Lippman, M. E., and Thompson, E. W. (2004) Pro-matrix metalloproteinase-2 transfection increases orthotopic primary growth and experimental metastasis of MDA-MB-231 human breast cancer cells in nude mice. Cancer Research 64, 652-658
  43. Cronin, K. J., Messina, A., Knight, K. R., Cooper-White, J. J., Stevens, G. W., Penington, A. J., and Morrison, W. A. (2004) New murine model of spontaneous autologous tissue engineering, combining an arteriovenous pedicle with matrix materials. Plastic and Reconstructive Surgery 113, 260-269
  44. von Heimburg, D., Kuberka, M., Rendchen, R., Hemmrich, K., Rau, G., and Pallua, N. (2003) Preadipocyte-loaded collagen scaffolds with enlarged pore size for improved soft tissue engineering. International Journal of Artificial Organs 26, 1064-1076
  45. Cassell, O. C., Morrison, W. A., Messina, A., Penington, A. J., Thompson, E. W., Stevens, G. W., Perera, J. M., Kleinman, H. K., Hurley, J. V., Romeo, R., and Knight, K. R. (2001) The influence of extracellular matrix on the generation of vascularized, engineered, transplantable tissue. Annals of the New York Academy of Sciences 944, 429-442
  46. Tanaka, Y., Tsutsumi, A., Crowe, D. M., Tajima, S., and Morrison, W. A. (2000) Generation of an autologous tissue (matrix) flap by combining an arteriovenous shunt loop with artificial skin in rats: preliminary report. British Journal of Plastic Surgery 53, 51-57
  47. Mian, R., Morrison, W. A., Hurley, J. V., Penington, A. J., Romeo, R., Tanaka, Y., and Knight, K. R. (2000) Formation of new tissue from an arteriovenous loop in the absence of added extracellular matrix. Tissue Engineering 6, 595-603
  48. Fernandes, D., Guida, E., Koutsoubos, V., Harris, T., Vadiveloo, P., Wilson, J. W., and Stewart, A. G. (1999) Glucocorticoids inhibit proliferation, cyclin D1 expression, and retinoblastoma protein phosphorylation, but not activity of the extracellular-regulated kinases in human cultured airway smooth muscle. Am J Respir Cell Mol Biol 21, 77-88
  49. Nakahara, H., Howard, L., Thompson, E. W., Sato, H., Seiki, M., Yeh, Y., and Chen, W. T. (1997) Transmembrane/cytoplasmic domain-mediated membrane type 1-matrix metalloprotease docking to invadopodia is required for cell invasion. Proc Natl Acad Sci U S A 94, 7959-7964
  50. Gilles, C., Polette, M., Seiki, M., Birembaut, P., and Thompson, E. W. (1997) Implication of collagen type I-induced membrane-type 1-matrix metalloproteinase expression and matrix metalloproteinase-2 activation in the metastatic progression of breast carcinoma. Lab Invest 76, 651-660
  51. Hickey, M. J., and Morrison, W. A. (1994) An improved matrix-type controlled release system for basic fibroblast growth factor. Biochem Biophys Res Commun 201, 1066-1071
  52. Goldberg, I., Knight, K. R., Mahoney, J. E., and O'Brien, B. M. (1993) A biochemical and histological comparison of vascularized and free fat grafts in the rabbit. Ann Plast Surg 30, 334-340